Before leaving on his second tour in Afghanistan, Marine Captain Sam Cahill, a leader, an athlete, a good husband and father, welcomes his screw-up brother Tommy home from prison. He'd robbed a bank. In country, Sam's helicopter is shot down and all are presumed dead. Back home, while Sam wastes away as a prisoner in a remote encampment, Tommy tries to take care of the widow and her two children. While imprisoned, Sam experiences horrors unbearable, so when he's rescued and returns home, he's silent, detached, without affect, and he's convinced his wife and brother have slept together. Demons of war possess him; what will silence them?

Some say that all houses have memories. For one man, his home is the place he would kill to forget. A family unknowingly moves into a home where several grisly murders were committed...only to find themselves the killer's next target. Successful publisher Will Atenton (Craig) quit a job in New York City to relocate his wife, Libby (Weisz), and two girls to a quaint New England town. But as they settle into their new life, they discover their perfect home was the murder scene of a mother and her children. And the entire city believes it was at the hands of the husband who survived. When Will investigates the tragedy, his only lead comes from Ann Paterson (Watts), a neighbor who was close to the family that died. As Will and Ann piece together the disturbing puzzle, they discover that the story of the last man to leave Will's dream house will be just as horrifying to the one who came next.

Following the tragic death of their two-year-old son Frankie, Irish couple Johnny and Sarah Sullivan and their remaining two offspring, 10 year old Christy Sullivan and 5 year old Ariel Sullivan, emigrate illegally to the United States via Canada with little in their pockets. Their final destination is Manhattan where Johnny hopes to work as a stage actor. They move into a unit in a run town tenement housed primarily with drug addicts, transvestites and one tenant coined "the man who screams". They do whatever they can to eke out a supportive family environment in this difficult situation, the support which ultimately extends to those around them, most specifically "the screamer" who turns out to be an African-American artist named Mateo with AIDS. But the memory of Frankie hangs over the family in good and bad ways, especially as Sarah learns she's pregnant. Christy...